Why Avoid Diphenhydramine?

When it comes to medications, especially those that can impact our cognitive and physical abilities, it’s crucial to be aware of the potential risks they pose. Diphenhydramine, commonly known as Benadryl, is a widely used antihistamine that comes with some considerations that should not be overlooked.

One of the primary reasons to exercise caution with diphenhydramine is its propensity to cause decreased reaction times and dizziness in individuals who take it. These effects can be particularly concerning in older adults who may already experience age-related declines in balance and coordination.

In older individuals who have additional medical conditions or physical impairments, the sedating effects of diphenhydramine can significantly increase the risk of falls or accidents. Particularly at night when getting up to use the bathroom, the combination of dizziness and decreased reaction times can be a dangerous mix.

Another worrying aspect of diphenhydramine use is its potential to increase the likelihood of bone fractures. Given that falls are already a common cause of fractures in the elderly, the additive sedative effects of this medication can further heighten the risk of sustaining such injuries.

Furthermore, diphenhydramine is known to have anticholinergic properties, which means it can block the action of acetylcholine, a neurotransmitter involved in many vital bodily functions. Prolonged use of medications with anticholinergic effects has been linked to cognitive decline and an increased risk of developing conditions such as dementia in older adults.

Individuals who are prone to urinary retention or have conditions like benign prostatic hyperplasia (BPH) should also exercise caution when considering the use of diphenhydramine, as it can exacerbate these issues by further relaxing the muscles in the bladder and urethra.

While diphenhydramine is generally regarded as safe for short-term use in treating symptoms like allergies or insomnia, its long-term use should be approached with care due to the potential for developing tolerance and dependence on the medication.

It’s essential to discuss any concerns or questions about diphenhydramine use with a healthcare provider, who can provide personalized guidance based on individual health considerations and potential interactions with other medications.

In conclusion, while diphenhydramine can offer relief from symptoms like itching or sneezing, it is important to weigh the potential risks associated with its use, particularly in older adults or individuals with underlying medical conditions that may increase susceptibility to its side effects.

Why Avoid Diphenhydramine?

Photo of author

Nancy Sherman

Nancy Sherman has more than a decade of experience in education and is passionate about helping schools, teachers, and students succeed. She began her career as a Teaching Fellow in NY where she worked with educators to develop their instructional practice. Since then she held diverse roles in the field including Educational Researcher, Academic Director for a non-profit foundation, Curriculum Expert and Coach, while also serving on boards of directors for multiple organizations. She is trained in Project-Based Learning, Capstone Design (PBL), Competency-Based Evaluation (CBE) and Social Emotional Learning Development (SELD).